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Air pollution linked to Diabetes: The 2016 global and national burden of diabetes mellitus attributable to PM2·5 air pollution

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1 August 2018 - 15:19, Tags: , , , ,

Air pollution linked to Diabetes

PM2·5 air pollution is associated with increased risk of diabetes; however, a knowledge gap exists to further define and quantify the burden of diabetes attributable to PM2·5 air pollution.

An article recently published in the Lancet, aims to define the relationship between PM2·5 and diabetes. The writers aimed to characterise an integrated exposure response function and to provide a quantitative estimate of the global and national burden of diabetes attributable to PM2·5.

Methods

The writers of the article did a longitudinal cohort study of the association of PM2·5 with diabetes. They built a cohort of US veterans with no previous history of diabetes from various databases.

Participants were followed up for a median of 8·5 years, and used survival models to examine the association between PM2·5 and the risk of diabetes. All models were adjusted for sociodemographic and health characteristics. Tests incldued a positive outcome control (ie, risk of all-cause mortality), negative exposure control (ie, ambient air sodium concentrations), and a negative outcome control (ie, risk of lower limb fracture).

Data for the models were reported as hazard ratios (HRs) and 95% CIs. Additionally, they reviewed studies of PM2·5 and the risk of diabetes, and used the estimates to build a non-linear integrated exposure response function to characterise the relationship across all concentrations of PM2·5 exposure.

Included were studies into the building of the integrated exposure response function if they scored at least a four on the Newcastle-Ottawa Quality Assessment Scale and were only included if the outcome was type 2 diabetes or all types of diabetes.

Also used was the Global Burden of Disease study data and methodologies to estimate the attributable burden of disease (ABD) and disability-adjusted life-years (DALYs) of diabetes attributable to PM2·5 air pollution globally and in 194 countries and territories.

Source material from the Lancet Planetary Health to read more click here

The Authors are:

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“…we found that the number of illnesses dropped around 80%. Further the nasty smell that dominated disappeared.” MOPU Superintendent